Discovery of Early Developmental Events in the Transition to Parasitism in the Hookworm Ancylostoma Caninum Using Genomic Technologies

Advanced in silico analysis of expressed sequence tag (EST) data for parasitic nematodes of major socio-economic importance - Fundamental insights toward biotechnological outcomes

S Ranganathan, R Menon, RB Gasser

2009-07-01

Parasitic nematodes infect humans, other animals and plants, and impose a significant public health and economic burden worldwide ..

A portrait of the "SCP/TAPS" proteins of eukaryotes - Developing a framework for fundamental research and biotechnological outcomes

C Cantacessi, BE Campbell, A Visser, P Geldhof, MJ Nolan, AJ Nisbet, JB Matthews, A Loukas, A Hofmann, D Otranto, PW Sternberg, RB Gasser

2009-07-01

A wide range of proteins belonging to the SCP/TAPS "family" has been described for various eukaryotic organisms, including plants ..

Improved insights into the transcriptomes of the human hookworm Necator americanus - Fundamental and biotechnological implications

EM Rabelo, RS Hall, A Loukas, L Cooper, M Hu, S Ranganathan, RB Gasser

2009-03-01

Hookworms of humans are blood-feeding parasitic nematodes of major socio-economic significance in a wide range of countries. They ..

Investigation of the regulation of transcriptional changes in Ancylostoma caninum larvae following serum activation, with a focus on the insulin-like signalling pathway

BJD Datu, A Loukas, C Cantacessi, P O'Donoghue, RB Gasser

2009-02-05

The exit from dauer in the free-living nematode Caenorhabditis elegans is under the control of a single amphidial neuron (ASJ) of ..

Exploring transcriptional conservation between Ancylostoma caninum and Haemonchus contortus by oligonucleotide microarray and bioinformatic analyses

C Cantacessi, A Loukas, BE Campbell, J Mulvenna, EK Ong, W Zhong, PW Sternberg, D Otranto, RB Gasser

2009-02-01

In this study, we identified, using an established oligonucleotide microarray platform for the parasitic nematode Haemonchus conto..

Needles in the EST haystack: Large-scale identification and analysis of excretory-secretory (ES) proteins in parasitic nematodes using expressed sequence tags (ESTs)

SH Nagaraj, RB Gasser, S Ranganathan

2008-08-01

Background: Parasitic nematodes of humans, other animals and plants continue to impose a significant public health and economic bu..

Gender-enriched transcripts in Haemonchus contortus - predicted functions and genetic interactions based on comparative analyses with Caenorhabditis elegans

BE Campbell, SH Nagaraj, M Hu, W Zhong, PW Sternberg, EK Ong, A Loukas, S Ranganathan, I Beveridge, RL McInnes, GW Hutchinson, RB Gasser

2008-01-01

In the present study, a bioinformatic-microarray approach was employed for the analysis of selected expressed sequence tags (ESTs)..

Transcriptional changes in the hookworm, Ancylostoma caninum, during the transition from a free-living to a parasitic larva

BJD Datu, A Loukas, P O'Donoghue, RB Gasser, SH Nagaraj, S Ranganathan, EK Ong, R McInnes

2008-01-01

Background: Third-stage larvae (L3) of the canine hookworm, Ancylostoma caninum, undergo arrested development preceding transmissi..

A transcriptomic analysis of the adult stage of the bovine lungworm, Dictyocaulus viviparus

S Ranganathan, SH Nagaraj, M Hu, C Strube, T Schnieder, RB Gasser

2007-09-05

Background: Lungworms of the genus Dictyocaulus (family Dictyocaulidae) are parasitic nematodes of major economic importance. They..

Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini

T Laha, P Pinlaor, J Mulvenna, B Sripa, M Sripa, MJ Smout, RB Gasser, PJ Brindley, A Loukas

2007-06-22

Background: Cholangiocarcinoma (CCA) - cancer of the bile ducts - is associated with chronic infection with the liver fluke, Opist..